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Exploring the Epigenetics Market: Opportunities for Product Placement and Innovation
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Report #09-003
Publication Date: July 2009
Page Count: 148
Print Copy: $3,200
Company-wide Electronic Copy (includes print copy): $5,200
plus Data Set: an additional $1,200
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Each member of The Science Advisory Board who participated in this study was invited to comment on the following questions. The responses, which have been edited for grammar and clarity, appear below along with each respondent’s job position.
Question 52. Do you believe that our fundamental understanding of epigenetics is outpacing the field’s ability to translate basic research to the clinic? Why or why not? (choose only one and please specify)
No
Yes
Don't know/not sure
Why or why not? (please specify)
No.
Complexity of biological pathways are mostly involved.
Post Doctoral Fellow / United States
No.
I don't think we have anywhere near the understanding of epigenetics that we think we do.
Post Doctoral Fellow / United States
No.
The ability to use microarrays increases the data output of epigenetics research. However, analyzing the tremendous amount of data and interpreting, on which mechanisms the results are based on, is still running behind.
Post Doctoral Fellow / Germany
No.
We are still in the early stage of doing genome-wide CHIP assay. The assay sensitivity and specificity will need to be further improved to identify more accurate markers with clinical usages.
Professor / United States
Yes.
Epigenetics data are just one-dimension of the big picture, i.e., the ability to put them in use in clinic. One has to use bioinformatics models to try and correlate all the information that comes from epigenetic studies into a three-dimensional scheme of pathways, interactions and relationships to figure out the outcome. Even then, one has to remember that in vitro and in vivo situations are like apples and oranges, and add the microenvironment into the models.
Staff Scientist / United States
Yes.
It is because basic epigenetics research has resulted in loads of information in different perspectives, some valued in translational medicine and some have to be proven for compatibility towards the clinic.
Professor / India
Yes.
The field of Epigenetics is very vast & crucial. Hence understanding the fundamentals of epigenetic changes are very important. However, when dealing with disease specific epigenetic data, they should be treated with caution since the epigenetic profile of an organism can be affected by many factors including therapy & environment.
Staff Scientist / United Arab Emirates
Don't know/not sure
I think there might be a tie. We still don't know enough about epigenetics and translational research has still a long way to go to be successful.
Post Doctoral Fellow / United States
And many more..
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