Life Science Industry Market Research

Meet a Panel Member

Dr. Feridoun Karimi-Busheri
NovaRx Corporation
Member since 2010

Dr. Karimi-Busheri is a Senior Investigator and Head of the Stem Cell Program at NovaRx Corporation.

Professional Background:
I work at NovaRx Corporation. NovaRx is a clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of novel cell-based therapeutic vaccines for the treatment of cancer.

Educational Background:
I received my Ph.D. in human genetics from the University of Wales, in the United Kingdom.

Professional Background:
In the past, I have worked as an Associate Professor at the University of Ahwaz, Iran. I have also conducted research at the University of Alberta in Canada. As a Senior Research Associate, I was able to investigate mechanisms of transformation and tumor progression.


Dr. Louis Ragolia
Winthrop-University Hospital Vascular Biology Institute
Member since 2010

Dr. Louis Ragolia is the Director at Winthrop-University Hospital Vascular Biology Institute. He is also an Associate Professor at Stony Brook University School of Medicine. Vascular Biology Institute is renowned for its research that focuses primarily on the pathogenic mechanisms responsible for the development of cardiovascular complications.

Educational Background:
Dr. Ragolia received his B.S. in Biochemistry from Stony Brook University. He also received his M.S. and Ph.D in Biochemistry from CUNY Graduate Center in New York.

Professional Background:
After completing his doctorate, Dr. Ragolia was an Adjunct Lecturer at Queens College from 1994-1997 and he held the same position at Stony Brook University until 1999. A year later, Dr. Ragolia became an Associate Professor at Stony Brook University; where he still teaches today. Some of his other achievements include appointments as Director of the Cell Biology Laboratory, Director of The Vascular Biology Institute, and Director of Biomedical Research Core at Winthrop University Hospital.


Dr. Robert Brown
US Department of Agriculture
Member since 2010

Educational and Professional background:
I received a Bachelors degree in Biology with a minor in Chemistry from Iowa Wesleyan College. The majority of my Biology courses were Plant-Science oriented. I was awarded graduate teaching assistantships to pursue masters and Ph.D. studies. My Masters studies were completed at University of Wyoming in Botany with a research emphasis in fungal taxonomy.

My interests in Mycology led me to pursue a Ph.D. in Plant Pathology, which I earned at Rutgers University. My research during masters and doctoral studies involved an approach which utilized morphological and protein profiling of fungi. I love working with fungi and also with proteins. While completing graduate studies I taught Science and Biology on a junior high and a high school level and I also taught Algebra at Seton Hall University. I also involved in teaching a summer course on Scientific Methodology to incoming freshman at Rutgers University as well as a required freshman course, Perspectives in Agriculture and the Environment.

Prior to completing a Ph.D., I worked as a County Agricultural Agent for Rutgers Cooperative Extension Service with the responsibility of administering an urban vegetable gardening program. A few years after I earned a Ph.D., I took a position as a postdoctoral research associate with USDA-ARS in New Orleans and after 4 years in this position, was hired permanently as a research plant pathologist by the same research unit, Food and Feed Safety Research. I have been in New Orleans a total of 20 years.


Dr. Vincenza Rita Lo Vasco
Sapienza University of Rome
Member since 2011

Dr. Lo Vasco is an assistant professor and principal investigator at Sapienza University of Rome where she works on analyzing gene expression of signaling molecules in tumor progression, with special regard to Phosphoinositide-specific Phospholipases C (PI-PLCs). She also collaborates with research groups  studying therapeutic use of stem cells in cardiac diseases.

Q:What is your professional title and what degree(s) do you hold?

VL: I received both my MD degree (1993, I was 23) and my specialization (1997) in medical genetics at Padua University and my PhD (2001-2004) at Bologna University. Before PhD, I worked at a hospital for 3 years as a clinical geneticist. I am an assistant professor and principal investigator at Sapienza University of Rome. I have been teaching human anatomy since 2003, and taught medical genetics and applied biology from 1998 to 2002.

Q: Please explain what your organization/institution does.

VL: The lab where I actually work is involved in neuromorphology and neuropathology studies. I am a PI in the genetics section and we analyze gene expression of signaling molecules in tumor progression, with special regard to Phosphoinositide-specific Phospholipases C (PI-PLCs). Recently, I started analyzing PI-PLCs in diseases other than nervous tumors. I also collaborate with prenatal diagnosis units, immunology and throat surgery sections, interested in inflammation.

Q: Please elaborate on your educational background.

VL: I attended humanistic studies, the high school was named Eschilo’s, so you can imagine: I studied Latin, Greek and so on. It is my family background, as my Mom is a latin and greek teacher. I studied at Padua Medical School where I graduated in medicine and specialized in medical genetics. I received my PhD in Human and molecular Morphological Sciences at Bologna Medical School. Both Padua and Bologna are ancient universities, and I love remembering the history of the places where I studied: from Vesalio to Harvey and much more.

Q: Please elaborate on your professional background.

VL: I worked a lot at Padua hospital: I was an undergraduate student in the section of Endocrine Surgery and my research work was about microsurgery of pancreatic islet transplantation in diabetic rats. Attending specialization courses, I worked as a clinical geneticist at Padua Pediatric Department and collaborated on research work about neurofibromatosis type 1 and retinitis pigmentosa. I worked 3 years at Treviso Hospital and my first occupation was epidemiology of biochemical screening of pregnancies. Then I moved to research. I went to Bologna, as a PhD student in Human and Molecular Morphological Sciences; I started studying signaling of phosphoinositides and PI-PLC beta1. It was a wonderful period; I worked a lot and learned a lot. I was offered an assistant professor position in Rome as soon as I finished my PhD, in 2004.

Q: What are your academic and professional interests?

VL: I am involved in the morphological analysis of fetal arterial vessels as a newborn project, and I collaborate with colleagues studying therapeutic use of stem cells in cardiac diseases, but the principal field of research is the signal transduction pathway of phosphoinositides. I analyze the gene expression of PI-PLC enzymes in different diseases, both human and experimental. I started with studying human leukemias, and this work is still going on in Bologna, and after that I studied rat astrocytoma. Actually, I am analyzing nervous system human diseases other than tumors and human endothelial cells. PI-PLCs are an intriguing family of enzymes, as they are 13 and strictly tissue specific. I hope that someone who studies PI-PLC biochemistry will collaborate with us, as our fields are gene expression and intracellular localization and we need more information to understand the role and the timing of action of isoforms. As I come from a clinical environment, my ability is to speculate about the relationship between specific diseases and some PI-PLC isoforms, so, in my last two publications, I hypothesized a role for PI-PLC eta2 in neuroblastoma, and in mental retardation associated with some chromosomal deletions. I hope my hypotheses will move clinicians to participate, although until now I have not seen many results, but I insist. One of my characteristics is willfulness, not always a good thing, but when you are a researcher sometimes it helps. We work a lot with fluorescence microscopy for morphology analyses and recently I am interested in protocols for technical amelioration of the methodology. I am a referee for the Italian University Ministry and of a committee of the European Research Council. I am also a reviewer of a number of journals, which requires a lot of time, but I am not able to refuse as I think these are different ways to contribute to scientific improvement.

Read more about Dr. Lo Vasco


Dr. Tim Sandle
Bio Products Laboratory Limited
Member since 2011

1. Professional title and degree(s)?

I am Head of Microbiology at Bio Products Laboratory Limited. I have a PhD, which centred on a study of global blood services and plasma fractionation.

2. Organization/Institution you are currently employed at (including department and any important distinctions about it)?

I am the site microbiologist for Bio Products Laboratory Limited, which is a pharmaceutical manufacturing and research organisation. BPL manufactures plasma derived products, such as large volume immunoglobulin used to treat people with weak immune systems and Factor VIII for haemophiliacs and other bleeding disorders.

My department consists of 25 graduate technicians. Some are involved in the assessment of the manufacturing environment, process water and product sterility testing. Others are involved in research and development into new microbiological methods (for which rapid methods are the key driver within microbiology at the moment). I also have a group who examine microbiological contamination problems and undertake risk assessments of the manufacturing process, based on the types and numbers of micro-organisms isolated.

3. Educational background (i.e., schools attended and field of study pursued)?

I undertook all of my studying by working and studying part-time (BS, MS and PhD) so this took longer than it would for the typical scientist. It was also tricky at times juggling work commitments and academic research!

I have worked in the microbiology field for most of my career (except for a very short time in parasitology laboratory). The key changes have been with the pace of technology: from laborious multiple dilution tests with incubation times of several weeks to automated methods with a far short time-to-result, especially during the past decade.

4. Professional background (i.e., other organizations/institutions you have worked for, awards, honors, etc.)?

All of my working life has been based in the UK. I have worked for the Medical Research Council, the National Blood Service, and at my current role at BPL.

I belong to three professional bodies: the Institute of Science and Technology, the Pharmaceutical Microbiology Interest Group, and I am a chartered biologist with the Society for Biology.

In terms of awards, I have received the Institute of Validation Technology paper of the year award for theoretical model for applying quality risk management to a pharmaceutical process.

Read more about Dr. Sandle


Dr. Anne Rascle
University Of Regensburg
Member since 2011

Dr. Anne Rascle is a Principal Investigator at the University Of Regensburg, whose research focuses on the molecular mechanisms of transcriptional regulation by STAT5 (Signal Transducer and Activator of Transcription) in normal and cancer cells


Q:What is your professional title and what degree(s) do you hold?
AR:  I am currently Principal Investigator at the University of Regensburg, financed by the Deutsche Forschungsgemeinschaft (DFG). I hold a PhD degree (in the field of Molecular and Cellular Biology, obtained in France, 1994) and completed the German Habilitation (Privat Dozent or PD degree, 2009) in Cell Biology (Faculty of Natural Sciences, University of Regensburg).

Q: Please explain what your organization/institution does.

AR: Since September 2010, I am an independent Group Leader whose research focuses on the molecular mechanisms of transcriptional regulation by STAT5 (Signal Transducer and Activator of Transcription) in normal and cancer cells. Although I am part of the Immunology department, I am not working on the regulation of the immune response. Rather, I have been generously offered lab space and access to equipment by the chair of the department, Prof. Daniela Männel.

Q: Please elaborate on your educational background.

AR: I grew up and attended school up to the Baccalaureate in a small French town (Oyonnax) before studying Biology at the University of Lyon (France).

I did my PhD at the renowned Ecole Normale Supérieure de Lyon (also attached to the University of Lyon) in the laboratory of Dr. Jacques Samarut, on the fascinating field of retroviral oncogenes (already focusing on mechanisms of transcriptional regulation).

Q: Please elaborate on your professional background.

AR: After my PhD, I did a Postdoc with Prof. David Hogness at Stanford University School of Medicine (as a Stanford Dean’s fellow), before joining the privately funded research institute DNAX (then part of Schering-Plough Pharmaceuticals, now acquired by Merck), in Palo Alto, California, first as senior Postdoc later as Principal Investigator. That’s where I initiated my current STAT5 research. I received twice an award as finalist to the DNAX Hajime Award.

In 2004, I moved with my family to Germany and joined the University of Regensburg as Research Associate. Unfortunately at that time, I did not have the opportunity to pursue my STAT5 research, and focused instead on characterizing the molecular mechanisms of transcriptional regulation by another factor, using the expertise acquired in the US. With this project and my previous STAT5 research, I completed the German Habilitation in 2009.

I had to wait until September 2010 to receive funding from the German Research Association (DFG) and start my independent research group… and finally return to my beloved research field (STAT5)!

Read more about Dr. Rascle


Dr. Jose-Luis Capelo-Martinez
University of Vigo at Ourense Campus
Member since 2011
1. Professional title and degree?
 
PhD in Analytical Chemistry, 2002. Awarded with as the best doctoral thesis in Chemistry defended at the University of Vigo in 2002.
 
2. Organization/Institution you are currently employed at?
 
Physical Chemistry Department at Ourense Campus
Science Faculty at Ourense Campus
University of Vigo at Ourense Campus
Campus de As Lagoas-Ourense
E-32004 Ourense
Spain
Phone + 34 610 835 903 
 
3. Educational background?
 
1987-1992 5-years degree in Chemistry (Analytical Chemistry). University of Santiago de Compostela-Spain.
1996-2002 PhD in Analytical Chemistry. University of Vigo-Spain.
 
4. Professional background (i.e., other organizations/institutions you have worked for, awards, honors, etc.)?
 
2002-2004 Postdoctoral research in Methal Speciation (developing of new methodologies). Centro de Química Estrutural. Instuto Superior Técnico. Universidade Técnica de Lisboa. Lisboa. Portugal.  
2004-2008 Research Fellow&invited lecturer at the REQUIMTE associated laboratory of the Department of Chemistry of the New University of Lisbon, Portugal.
2008-To date, Research Fellow. Faculty of Sciences at Ourense Campus. University of Vigo at Ourense Campus. As Lagoas s/n 34002. Ourense. Spain.
 
Awarded with as the best doctoral thesis in Chemistry defended at the University of Vigo in 2002.
 
5. Academic/Professional interests  (i.e., description of your research projects, committees you serve on, etc)?
 
Development and validation of analytical procedures for: trace metals, metal speciation, proteomics, biomarker discovery, food chemistry. Analytical techniques: HPLC-ICP-MS, ET-AAS, F-AAS, CV-AAS, HG-AAS, HG-AFS, MALDI-TOF-MS/MS, RP-HPLC-ESI-IT-MS/MS. Member of the Royal Society of Chemistry. Founder of the International Congress on Analytical Proteomics (http://sing.ei.uvigo.es/ICAP/) and Founder of the Journal of Integrated -OMICS. (www.JIOMICS.com).
 
6. Outside interests (i.e., sports you enjoy, hobbies, outside activities, etc.)?
 
European Rugby, Basketball, Chess.
 
7. Please describe your motivations as to why you wanted to go into the scientific field -- what were your motivations or inspirations?
 
To try to better understand how God thinks through using the gift He gave us: the intelligence.

Dr. Urmila Shirwadkar
Radiation Monitoring Devices, Inc
Member since 2011
1. Professional title and degree?
 
I am working as a scientist at a research company ‘Radiation Monitoring Devices, Inc.’ (RMD), located in Watertown, Massachusetts. I completed my PhD in Physics and Applied Physics from the University of Massachusetts Lowell (UML) in 2009. 
 
2. Organization/Institution you are currently employed at?
 
I am working in the advanced materials group at RMD to develop novel radiation detectors for various nuclear science applications.
 
3. Educational background?
 
In 2001, I received my MS degree in Physics from University of Mumbai, India. I explored the teaching profession in India for about two years. I worked as an electronics teacher for close to two years at a degree college in Mumbai (SIES college of Arts and Science). I was mainly teaching electronics and instrumentation to junior college students. Subsequently, I pursued further research in Physics in the United States. I worked in the Heavy-Ion Spectroscopic Investigations (HI-SPIN) group at the University of Massachusetts Lowell (UML) over the summer of 2003, and got a flavor of the very exciting experimental nuclear structure research. The necessary background in nuclear physics and the hands-on laboratory training at UML led me to enroll into the PhD program in Nuclear Physics at the University of Massachusetts Lowell in Fall 2003. I completed my second master’s degree from UML, and was conferred a doctoral degree in 2009. During my graduate years my training was mainly in the field of experimental nuclear physics, and nuclear instrumentation. After I joined the PhD program at UML, I was a teaching assistant, conducting laboratory sessions for the first year Physics students. 
 
4. Professional background?
 
In a collaborative effort between UML and Argonne National Laboratory (ANL), I have participated in many experiments at ANL, which houses the state of the art infrastructure involving heavy-ion accelerator ATLAS, and gamma-ray spectrometer Gammasphere. These DOE funded experiments to study nuclei at high angular momentum are highly complex continuous runs over a few days to week/s.  The experimental multi-parameter data collected at ANL were analyzed at the University of Massachusetts Lowell. I have presented the research work at various American Physical Society (APS), Division of Nuclear Physics (DNP) meetings, and published in prestigious peer-reviewed journals such as Physical Review Letters (PRL). I was awarded as 2009 Sciences Graduate Research Scholar of the year, by the Society of Sigma Xi, UMass Lowell chapter. My current position a scientist at RMD for the past two years has allowed me to expand my expertise to the field of radiation detector development for various nuclear monitoring applications. 
 
5. Academic/Professional interests?
 
As a scientist at RMD, the primary interest is to develop novel scintillation and semiconductor detectors for homeland security, various noninvasive medical applications (example: SPECT, PET), and fundamental nuclear physics research experiments.  My current work specifically involves characterizing scintillation materials by testing them for their use as potential cost-effective radiation detectors for medical imaging and nuclear non-proliferation applications.
 
6. Outside interests?
 
I enjoy traveling and exploring different places. I also like to listen to music, participate in dances, and play tennis.
 
7. Please describe your motivations as to why you wanted to go into the scientific field -- what were your motivations or inspirations?
 
Atomic nucleus is a complex many-body system consisting of protons and neutrons. The primary motivation lies in the fact that information about nuclear shape and symmetry provides valuable insight into the structure of a nucleus. Understanding the structure of heavy actinides provides answers to many fundamental questions in science such as the very existence of superheavy nuclei and magic shell gaps. As a part of my MS and PhD, I explored rare earth and heavy actinide nuclear chart regions, focusing on the exploration of shape-coexistence and metastable states (isomers) in nuclei. Nuclei are well deformed in the region of rare earths and heavy actinides, hence are most suitable to explore these phenomena. These experiments are crucial in identifying the next neutron and proton magic shell gaps. 
 
 
As a part of my M.S. thesis, I investigated the prolate-to-oblate shape transition in hafnium nucleus, in collaboration between UML, ANL, and Rochester University. A state-of-the-art gamma-ray spectrometer- Gmmasphere consisting of 110 high purity Ge detectors was used in conjunction with a heavy-ion particle detector CHICO to reconstruct the kinematics. My PhD dissertation enabled a discovery of new metastable states in 246, 248Cm nuclei. The experimental information in the Z > 100 mass region and heavy actinides is very sparse due to experimental limitations arising from huge fission backgrounds. The energy information of the underlying orbitals of the isomers in 246, 248Cm allow direct comparison with theoretical models, verifying accountability of the model predictions of the superheavy nuclei. These results provide valuable input for different models, which are crucial in predicting the island of stability beyond known magic shell-gaps at Z = 82 and N = 126. 
 
My current research is more application based requiring strong background in experimental gamma-ray spectroscopy. The motivation comes from the fact that my research directly impacts public health and safety. It has a major impact on health care by developing novel scintillators suitable for various medical imaging applications such as Computed Tomography (CT), SPECT, X-ray imaging, and PET. My research also has a major impact on national safety. Gamma-ray signatures are generally used for detecting nuclear materials. It is difficult to distinguish gammas from backgrounds and innocent radiological materials, which can result in high false alarm rate. Some applications viz. detecting illegally trafficked nuclear materials, require simultaneous detection of both neutron and gamma radiation. Dual neutron-gamma detectors have a potential to reduce the false alarm rate. Conventionally this is accomplished with a combination of two detectors registering neutrons and gammas separately. At RMD as a key team member, I am dedicated to developing new nuclear detection materials for dual gamma-neutron detection to replace He-3 tubes, in the light of its worldwide shortage. 
 

Dr. Xavier Sagaert
University Hospitals Leuven
Member since 2011
 
Q1. Please explain what your organization/institution does?
 
The major function of the Department of Pathology of the University Hospitals Leuven is the diagnosis of tumors, evaluation of prognostic indicators, and the guidance of individualized therapy by molecular tests. The Department of Pathology accomplishes this mission in three different areas:
Diagnosis : the diagnostic services of the Department of Pathology (morphology, immunohistochemistry and molecular pathology) are the backbone of patient management and also contribute significantly to basic and clinical research. Although a large portion of the clinical workload depends on the activity of the clinicians of the University Hospitals Leuven, our outside consultative service has continued independently to increase over the years.  
Research : our research lab plays a pivotal role in fostering interdisciplinary collaboration in research, thus translating advances in basic science into innovative approaches in clinical practice. We have an outstanding and leading international reputation in the field of cancer research (with emphasis on lymphomas, melanomas and carcinomas), and are part of a long-standing collaboration, reflected by many previous projects and publication records.
Education : a major task of the Department is education of pre- and postgraduate medical and bioscientific students. We are proud to offer the largest pathology residency program of Belgium
 
 
 
Q2. Please elaborate on your educational background?
 
In 2000, after training in both Belgian and South African hospitals, obtained my MD degree with cum lauda at the University of Leuven, Belgium. I was educated as a pathologist at the University Hospitals Leuven and obtained my PhD, entitled “Molecular Genetic Analysis of MALT Lymphomas” in 2007, also at the University of Leuven in a combined MD/PhD program. In 2005, I was awarded the H. Van Waeyenbergh and Herbert Hoover Fellowship granted by the Belgian American Educational Foundation for Cancer Research at New York University Medical Center. And in 2010, I followed several research & lecture fellowships at the University of British Columbia (Vancouver), Mount Sinai Hospital (Toronto), and Weill Cornell Medical College (New York), sponsored by the FWO (Fonds voor Wetenschappelijk Onderzoek, Flanders) and the Fullbright Comission for Education Echange between the USA, Belgium and Luxembourg, respectively.    
 
 
 
Q3. Please elaborate on your professional background?
 
Since 2009, I have been a full staff member at the Pathology Department of University Hospitals Leuven, where I am also responsible for the residency program. Also since 2010, I am a senior clinical investigator of the FWO (Fonds voor Wetenschappelijk Onderzoek, Flanders).  
 
 
 
Q4. What are your academic and professional interests
 
My current research interests are gastrointestinal malignancies and (non)-Hodgkin lymphomas. I am leading and participating to several projects which focus on :
the pathogenesis of B- and T-cell non-Hodgkin’s lymphomas
identification and role of genetic aberrations in lymphomas
genetic profiling of gastrointestinal cancers
characterization of the immune/stromal responses that surround cancers (host-versus-cancer response).
PubMed Search for Articles.
 
Q5. What are some of your outside interests?
 
I like to travel as much as possible, and enjoy walking in the outdoors, literature and movies. I have a passion for architecture. Most of all, I like it to spend quality time with my close friends and family.
 

Dr. Carlos Lodeiro Espiño
University of Vigo, Faculty of Science at Ourense campus, Spain
Member since 2011
Q1. What is your professional title and what degree(s) do you hold?
Dr. Lodeiro is a Senior IPP Researcher-Lecture and Co-Head of the BIOSCOPE  Research Team together with Dr. Jose Luis Capelo, in the University of Vigo, Faculty of Science at Ourense campus, Spain (www.bioscopegroup.org). 
 
Q2. Please explain what your organization/institution does (including department and any important distinctions about it)?
 
I work at the Faculty of Science at Ourense Campus, in the Physical Chemistry Department of the University of Vigo(NorthWest Spain). Our group, BIOSCOPE, is devoted to  pushing science beyond its present limits. Our research includes new strategies in sample treatment for proteomics, biomarker discovery and mass spectrometry imaging of tissue samples as well as in the synthesis and applications of emissive chemosensors and nanoparticles for recognition, separation and quantification of metal ions, anions, peptides, proteins and short organic molecules for in vitro and in vivo studies. 
 
Q3. Please elaborate on your educational background (i.e., schools attended and field of study pursued)?
 
I received my Ph.D. in Inorganic Supramolecular Chemistry from the University of Santiago de Compostela, Spain in 1999. 
 
Q4. Please elaborate on your professional background (i.e., otherorganizations/institutions you have worked for, awards, honors, etc.)?
 
Since 1999 to 2008 I worked as Invited Assistant Professor at the Chemistry  Department of the University NOVA of Lisbon, and as Assistant Researcher in the  REQUIMTE FCT-UNL (Science and Technological Portuguese Network), in Portugal,  with short training periods at the University of Bologna (Italy) and University of Strasbourg (France). 
 
Q5. What are your academic and professional interests  i.e., description of your research projects, committees you serve on, etc)?
 
My research as a Marie-Curie fellow on the Photochemistry group of the FCT-UNL  was focused on Molecular Level Devices and Machines, and Chemosensors (Coord. Chem. Rev., 253, 1353-2635, 2009). In 2005, The BIOSCOPE team started at the REQUIMTE, FCT-UNL. Once I returned to Spain in 2008, I collaborated with international companies and different Hospitals from Spain and Portugal, and with financial support granted by the local government (Xunta de Galicia), the Spanish government and various European agencies. The BIOSCOPE team´s research was directed towards medical proteomics, focusing in tuberculosis, arthritis and cancer studies(Electrophoresis, 31, 3407-3419, 2010; J. Proteomics, 73, 1411-1414, 2010). 
 
To meet this challenge we have set the goal of developing new methodologies in sample treatment for Proteomic studies including the application of fluorescent markers and nano-particles for separation and quantitation of peptides and proteins via mass spectrometry-based technologies (J. Proteome Res., 7, 2097-2106, 2008). 
 
Parallel to this research, new peptides and fluorescent amino acids as new emissive and colorimetric probes have been designed and synthesized for functionalization of several metallic and non-metallic nanoparticles for their use as in vitro and in vivo probes. 
(Chem. Soc. Rev., 39, 2948-2976, 2010) 
 
I am member of various scientific societies as well as member of the editorial board of several publications, including, but not limited to: The Royal Society of Chemistry and The Portuguese Society of Chemistry. I am also the co-founder and one of the editorsin-chief of the Journal of Integrated OMICS (www.jiomics.com), and member of the editorial Board of the Global Journal of Inorganic Chemistry and of the Sensors and transducers journal. Our group has strong background in the organization of international research events for technological transfer in the areas related to our lines of research, such as hands-on courses and training courses (a la carte). The most notable events were organized between 2008 and 2010, namely the first, second and third edition of the “Hands-on course on Proteins and Proteomics” held in the Campus of Caparica, University NOVA of Lisbon in 2008, 2009 and 2010. In addition in 2010 and 2011, two editions of the Hands-on course in sample treatment for proteomics were held in the Ourense Campus at the University of Vigo. I would like to mention the Organization of the International Conference on Analytical Proteomics “ICAP”, held in Costa de Caparica, Portugal, in September, 2009. Our group, are organizing the second edition again next July 2011, in Spain. In the first edition, 160 attendees from 26 countries participated in the event and this second 230 attendees from 30 different  countries are registered. For further details visit the web page: http://sing.ei.uvigo.es/ICAP/ 
 
Q6. What are some of your outside interests (i.e., sports you enjoy, hobbies, outside activities, etc.)? 
 
Painting is other aspect in my life to relax and express creation, but unfortunately during the last years it has become difficult to share the time between Science and Art interests. Travels and walking are also my hobbies. 
 
Q7. Please describe your motivations as to why you wanted to go into thescientific field --what were your motivations or inspirations? 
 
I guess that the innate human curiosity, unraveling the unknown is the driving force which pushed me to become scientist. In my opinion, the human mind is a supramolecular combination of curiosity, creativity and passion. Without one of these ingredients, science would not be possible. As Marie Curie used to say: "A scientist in his laboratory is not a mere technician: he is also a child confronting natural phenomena that impress him as though they were fairy tales."

Dr. Ali Mobasheri
The University of Nottingham
Member since 2004

Dr. Ali Mobasheri is an associate professor at The University of Nottingham.

Q: What is your professional title and what degree(s) do you hold?

AM:I am an Associate Professor and Reader in Comparative Physiology in the School of Veterinary Medicine and Science at the University of Nottingham1. A “Reader” is a unique academic post in the United Kingdom and is equivalent to an “Associate Professor” in North America.

Q: What does your organization/institution do?

AM: The University of Nottingham is often described as a “Global University”. The University of Nottingham was described as the 10th best university in the UK by the Shanghai Jiao Tong world rankings index, placed in the top one percent of all universities worldwide by the Times Higher Education-QS World University Rankings 2009 and ranked 74th in the World by the QS World University Rankings2. Nottingham is affiliated with the Russell Group3, Universitas 214 and the Association of Commonwealth Universities (ACU5). In 2008 the Research Assessment Exercise (RAE6) carried out by the UK government confirmed Nottingham as the country’s 7th most powerful research university. Ninety percent of all research at Nottingham was described as being of 'international standard', with 60 percent classed as 'world-leading' or 'internationally excellent'.

The School of Veterinary Medicine and Science is the newest, purpose-built veterinary school in the United Kingdom for over 50 years. It was established to make significant contributions to research and teaching within the context of companion animal, production animal and human health. Research is central to the activities of the vet school, both in terms of maintaining ourselves at the forefront of national and international efforts in veterinary medicine but also as an integral part of the training and education for undergraduate and postgraduate students. The vet school has a dynamic, vibrant and highly stimulating teaching and research environment, which is achieved through an international blend of students and researchers who are committed to innovative learning and scientific discovery.

The academic staff of the vet school work within 5 strategic research areas: Infection and Immunity; Population Health and Welfare; Comparative Medicine; Reproductive Biology and Veterinary Educational Research. Our research is closely aligned with that in the School of Biosciences with whom we share some research facilities and equipment. The involvement of our Clinical Associates and other organisations within our research programs enables the identification of clinical problems in the field and the rapid application of investigational science to these problems in both production and companion animal species.

In the 2008 Research Assessment Exercise, the School of Veterinary Medicine and Science joint submission with the School of Biosciences was ranked first in the country for the power of its research with 95% of its activities classified at an international standard.

I am the head of the Musculoskeletal Research Group in the vet school and lead an active and productive research group focusing on various aspects of cartilage and tendon inflammation, stem cell biology and chondrocyte cell physiology. My research group is actively working within the “Comparative Medicine” research area in the vet school. My proven track record of professional achievement is backed up by over 120 primary publications in peer-reviewed scientific journals. I have published 12 book chapters and have another 8 submitted or in press.

I currently serve on the University of Nottingham’s Ethical Review Committee (ERC). I served as the Postgraduate Sub-Dean in the vet school from February 2007 to July 2011 and had responsibility for the development and implementation of postgraduate programmes in the school. I was also a member of the vet school's Research Directorate (now called Research Committee) from February 2007 to July 2011. 

Q: Please elaborate on your educational background

AM: I was educated at primary and junior high school levels in Tehran from 1975 to 1983. I moved to the UK in 1983 and attended senior high school in South London. I attended Cannock School in Kent from 1983 to 1985 and later moved to Dulwich College in London from 1985-1987. I was admitted to Imperial College London where I studied Biochemistry from 1987-1990. I graduated from Imperial College with a Bachelor of Science degree (with Honors) in 1990. I then took up an Open Fellowship at the University of Toronto in Canada and completed a three-year Master's degree in Physiology and Biochemistry. In 1993 I returned to the UK to undertake doctoral level research funded by the Arthritis Research Campaign in Molecular and Cellular Physiology at Wolfson College Oxford. I graduated from the University of Oxford in March 1997. Shortly after completing my Doctor of Philosophy degree in 1997 I joined the School of Biosciences at the University of Westminster as a Lecturer in Biomedical Sciences. After three years in London I moved to the Faculty of Veterinary Science at the University of Liverpool as Lecturer (2000-2005) and then Senior Lecturer (2005-2006) in Veterinary Biology. I joined the University of Nottingham in September 2006.

Q: Please elaborate on your professional background

AM: I have been active in several scientific societies including The Biochemical Society (UK), The Physiological Society (UK), The American Physiological Society, The Biophysical Society, The Orthopaedic Research Society, The British Society for Matrix Biology (BSMB) and the Osteoarthritis Research Society International (OARSI). Most of my current society involvement is in OARSI.

My contribution to veterinary research was recognized in 2004 when I was awarded the George Fleming prize, the highest award given by The Veterinary Journal (Elsevier) in recognition of research that has made the greatest contribution to scientific and veterinary knowledge.

I currently serve on the editorial boards of 12 International journals including Histology and Histopathology (Cellular and Molecular Biology7 ), The Veterinary Journal8, Journal of Applied Bioscience9, Recent Patents on Regenerative Medicine10 , Recent Patents on Biomarkers 11, Current Rheumatology Reviews 12, Biosensors 13, Alternative Medicine Studies14, Frontiers in Bioscience15, Frontiers in Physiology 16, World Journal of Stem Cells17, World Journal of Orthopaedics18 .

In June 2010 I was invited to edit a Special Issue on Veterinary Biomarkers for the Veterinary Journal and I am currently editing two Special Issues for Frontiers in Bioscience and Frontiers in Physiology.

Q: What are some of your academic and professional interests?

AM: My research interests are wide-ranging but I am mainly recognized for my work on the cellular physiology of articular cartilage as well as the study of membrane proteins such as aquaporins. I have extensive experience of international scientific collaboration. I have collaborators in Germany, Belgium, France, Spain, Portugal, the Netherlands and the United States. I have had a number of studentships and project grants from Research Councils in the UK. I have also led projects in collaboration with industry. I have ongoing collaborations with industry in the UK (Mars ®, Melton Mowbray), Europe (Bioiberica SA) and the United States (Aviva Systems Biology, San Diego, California). I have collaborated with leading academic investigators in the area of cartilage cell biology in established international centres of excellence in Europe and the United States. I have contributed to the development of high quality research and teaching and provided professional consultancy services for healthcare, veterinary, diagnostics and pet food industries in the UK.

Committees I serve on:

I have been a member of the Communications Committee of the Osteoarthritis Research Society International (OARSI) over the last 5 years and I have built an extensive network of academic and industrial researchers.
In 2011 I was appointed as a member of the Biotechnology and Biological Sciences Research Council’s “Pool of Experts” to assist with the peer review of grant applications submitted for funding – this is rather like the roles fulfilled by individuals appointed to serve as members of NIH Study Sections.

Career Goal:

My goal is to continue conducting internationally recognized research, contribute to the development of high quality teaching as well as professional consultancy services for healthcare, veterinary, diagnostics and agri-food industries.

Q: What are some of your outside interests?

AM: I run five miles three times a week to keep fit. I also enjoy cycling and swimming. I am passionate about world history and like to read books pertaining to world civilizations and how empires rise and fall. I am interested in the causes and consequences of political conflict and war and why the fallible human race does not seem to learn from history.

My favourite places to visit are the British Museum and the Natural History Museum in London. I like travelling and frequently combine international conferences with short breaks and cultural visits. Florida and California are my favourite travel destinations.

Q: Pease describe your motivations as to why you wanted to go into the scientific field -- what were your motivations or inspirations?

AM: My interest in the natural world combined with my curiosity about what makes up living things and how living cells work inspired and motivated me to follow a career in research. I love my work and spend a lot of my time doing microscopy. I hope that I will be able to do research after I retire.


Sabri Bora Erdemli
PhD2Consulting
Member since 2012

Mr. Sabri Bora Erdemli is currently Co-Founder and Director of PhD2Consulting. He is also completing his doctoral degree at Johns Hopkins University School of Medicine.

Q: What is your professional title and what degree(s) do you hold?

SE: I am Co-Founder and Managing Director at PhD2Consulting. I am also a Ph.D candidate at Johns Hopkins University School of Medicine. Finally, I am an active Board Member at the American-Turkish Association of Washington, DC.

In addition to my professional titles, I hold three other degrees: a Master of Arts in Biophysics, a Master of Science in Computational Sciences and Engineering, and a Bachelor of Science in Chemical Engineering.

Q: What does your organization/institution do?

SE: Enzymes play a key role in all metabolic and cell-signaling processes. Characterization of an enzyme’s biological function must include the description of its mechanisms at an atomic level. Our laboratory is deciphering the catalytic mechanism of several enzyme families, using a combination of molecular biology, biochemistry, and structural Biology.

Q: Please elaborate on your educational background.

SE: While studying for my Ph.D. in Biophysics and Biophysical Chemistry at Johns Hopkins University School of Medicine, I discovered the mechanism of a key enzyme and developed inhibitors, which could potentially shorten the length and decrease the cost of tuberculosis treatment.

For my M.A. in Biophysics, also at Johns Hopkins University, I researched Quantum mechanical and Molecular Mechanical (QM/MM) calculations of redox reaction in Quinone Oxidoreductase.

My M.Sc. in Computational Science and Engineering, from Koc University in Turkey, focused on developing and implementing a novel computational method to identify important components of protein-protein interactions that could decrease the exorbitant cost of drug discovery studies.

Finally, for my B.Sc. Chemical Engineering, I concentrated on investigating the effect of oxygen level on protein production of recombinant bacteria and designed a lab-size bioreactor for enzyme production.

Q: Please elaborate on your professional background.

SE: In February 2011, my business partner Joel Hooper, Ph.D. and I founded PhD2Consulting. At PhD2Consulting, we strive to provide insight and networking opportunities for Ph.D. candidates and professionals who are interested in transitioning from academia to management consulting. We have nearly 1,000 LinkedIn members and a growing network of motivated Ph.D.’s eager for information about careers in consulting.

Q: What are some of your outside interests?

SE: Outside my professional activities, I try spending most of my time with my family and two year old daughter. I am also an avid soccer fan who follows national and international soccer very closely.

Q: Please describe your motivations as to why you wanted to go into the scientific field -- what were your motivations or inspirations?

SE: My biggest motivation going into the scientific field was my endless hunger for learning.


Dr. James Harris
Immunology Research Centre
Member since 2001

Dr. Harris is Programme Manager for the Immunology Research Centre in Ireland.

Q: What is your professional title and what degree(s) do you hold?

JH: I am Programme Manager for the Immunology Research Centre, based at Trinity College Dublin. I have a BSc (Hons) in Zoology and a PhD in immunology.

Q: What does your organization/institution do?

JH: The Immunology Research Centre, (IRC), is a Science Foundation Ireland (SFI) funded Strategic Research Cluster, which involves 10 separate Immunology labs, all based in Trinity College or NUI Maynooth. The IRC also has two industrial partners, Opsona Therapeutics, based in Ireland, and Merck (formerly Organon/Schering Plough). The aim of the IRC is to identify and characterise endogenous and exogenous immunomodulatory molecules that regulate inflammatory responses, with a view to developing new therapeutic treatments or vaccine adjuvants. You can find out more at:

http://www.tcd.ie/Biochemistry/irc/

Q: Please elaborate on your educational background.

JH: My BSc degree was from Nottingham University in the UK. I originally had a strong interest in animal behaviour, but slowly drifted towards immunology during the degree. I then did a PhD at the University of the West of England, looking at the role of two hormones, (melanin-concentrating hormone and α-melanocyte stimulating hormone), in immune regulation in rainbow trout. From that point on it was all immunology!

Q: Please elaborate on your professional background.

JH: My first postdoctoral position was at the Institute for Animal Health in Compton, Berkshire in the UK. I worked on immune responses to respiratory syncytial virus (RSV) in cows. From there I moved on to Oxford University (The Sir William Dunn School of Pathology) for a postdoctoral position looking at macrophage receptors and a (then) novel molecule called carboxypeptidase, vitellogenic-Like (CPVL). It didn’t set the scientific world alight, but was a good grounding in macrophage biology (working with Professor Siamon Gordon) which has been a consistent feature of my research career since. I then took a postdoctoral position at the University of New Mexico, based in Albuquerque, working on the role of autophagy in the response of macrophages to infection with Mycobacterium tuberculosis. After this I moved back to Europe and settled in Dublin, Ireland, where I have been for the past 6 years. I have worked as a Postdoctoral Fellow on projects looking at the effects of TNF-blockers on macrophage responses to mycobacteria and the role of autophagy in cytokine secretion. I now have a position as Programme Manager/Senior Scientist and I am semi-independent – leading my own research on macrophage biology.

Q: What are some of your academic and professional research interests?

JH: As I have already mentioned, my main scientific interests are in macrophage biology. More generally, I have a strong interest in inflammation in autoimmune and infectious diseases. I am specifically interested in the regulation of inflammation by autophagy, a homeostatic mechanism by which cells can remove and degrade intracellular constituents, including organelles. I’m still a fairly early-career scientist, so I’m not on any important committees, but I am slowly ingratiating myself into the field...

Q: What are some of your outside interests?

JH: I love most sports, but particularly football (soccer) and squash, although I don’t get as much time to play either these days! I like photography (particularly wildlife) and I play the drums – a great way to release those frustrations from the lab! I read a lot and have just bought a new mountain bike, which will keep me busy in my spare time. I also love skiing (despite recently dislocating my shoulder at a Keystone Conference…) and scuba diving. Unfortunately these are two of the most expensive hobbies and I am a (mid-level) academic scientist, so I don’t get to do either much…

Q: Please describe your motivations as to why you wanted to go into the scientific field -- what were your motivations or inspirations?

JH: My original motivation was a desire to be a zookeeper! I loved (and still do) animals and just wanted a job that involved working with them. As I got further into my BSc degree, I realised that there was a lot more to animal science and started to look at physiology and immunology. My PhD, in my mind, a compromise between immunology and zoology – the fact it was in fish made it less scary! After that, I was sold on the whole immunology thing and my motivation now is really just to keep doing what I do. I never get tired of discovering new things (however small or insignificant). It’s when serendipity strikes and you discover something quite by accident – that’s what keeps me motivated. You genuinely never know what your big finding will be. And while scientists can be a pretty cynical bunch, the enthusiasm of the people around me (especially here at Trinity) is infectious. I don’t worry too much about whether my discoveries will change the world; I just like to keep challenging (and surprising) myself. Maybe one day I’ll make that truly earth-shattering discovery, but in the meantime I’m having fun and hopefully doing some good. Of course, those days when you run your Western blot the wrong way, or drop your ELISA plates, or the microscope blows up, can put a bit of a dampener on one’s enthusiasm…


Dr. Bouzid Menaa
Fluorotronics, Inc.
Member since 2011

Dr. Bouzid Menaa is a R&D consultant and Research Program Director in bionanotechnology at Fluorotronics, USA. He is also a visiting Research Professor at the University of Annaba, Algeria.

Professional Background:
I am R&D consultant and Research Program Director in bionanotechnology at Fluorotronics, USA (Fluorotronics.com). The company has developed a recently patented bioanalytical technology known as fluoro-Raman Spectroscopy for theranostics and diagnostics. We have published several articles on the utilization of this technique for biomedical and pharmaceutical applications. The technique is sensitive, quantitative and is based on pulsed laser irradiation permitting the detection of carbon-fluorine signal with high resolution. The development of fluoro-therapeutics and fluoro-biomolecules due to the importance of fluorine properties in life sciences is a major challenge. In addition, fluoro-molecules can be used as biomarkers to study biomolecular interactions.

In parallel, I am also a visiting Research Professor at the University of Annaba, Algeria where I am investigating biomolecules/surfaces interactions for the prevention and inhibition of bacterial biofilms.

Educational Background:
I obtained a Masters Degree in Organic Chemistry at the University of Rouen, France, and worked at the Research Institute in Fine Organic Chemistry (IRCOF) in Heterocyclic Chemistry for the development of novel biomolecules. Thereafter, I carried out my Ph.D in Materials Chemistry at St-Andrews and Birmingham University,UK, where I developed and studied the properties of new layered organic-inorganic hybrid mixed-metal phosphonate materials and metal-organic frameworks for applications as selective sorbents and heterogeneous catalysts.

Professional Background:
After my Ph.D, I joined the Laboratory of Inorganic and Photonics Materials at Kyoto University; first, as a Centre of Excellence Research Fellow to carry several projects on polymeric and sol-gel-derived organic-inorganic hybrid glass films doped with optically active dyes for integrated optics and photonic applications. Then, I obtained a Japan Science and Technology (JST-Presto) fellowship with Professor Takahashi to develop and improve the durability of new phosphate glass systems with low glass transition temperature for laser grating and applications as functional active optical devices. As a specialist of sol-gel glass, I extended the applications of these materials for bio-applications.

As a Research Associate at San Jose State University, CA, USA, I designed and developed new transparent nanoporous sol-gel glasses in order to study the proteins conformation and biological activity of encapsulated and adsorbed proteins in crowded and hydrophobic environment. I developed several collaborations worldwide and the research was crowned by high impact scientific publications. Thereafter, I joined the University of Liege, (Belgium), as scientific collaborator with projects focusing on Atomic Force Microscopy and single molecule force spectroscopy as a tool for molecular recognition, (DNA single strands hybridization and interactions with ligands).


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